Francisco Varela portrait photograph

Francisco Varela (1946-2001) was a Chilean biologist, philosopher, and cognitive scientist who developed theories of autopoiesis and enactive cognition. His work integrated biological research with contemplative traditions to examine the nature of life and consciousness.

Working with Humberto Maturana, Varela developed the theory of autopoiesis - the process by which living systems continuously create and maintain themselves through recursive interactions with their environments. They proposed that life involves co-creation of organism and world through ongoing structural coupling rather than simple adaptation to pre-existing conditions.

Varela’s concept of “enactive cognition” suggested that mind emerges through embodied action and interaction with environments rather than representing an independent world. This perspective proposed that consciousness evolved through creative processes of world-making. His research on neural networks, immune systems, and emergence examined how complex behaviors arise from interactions between system components.

In later work, Varela collaborated with Buddhist contemplatives to study the neural correlates of meditative awareness, integrating first-person contemplative investigation with third-person scientific research. He co-founded the Mind & Life Institute with the Dalai Lama to facilitate dialogue between Buddhist philosophy and cognitive science.

Varela held positions at the University of Chile, University of Colorado, and University of Paris. He published extensively with Humberto Maturana, Evan Thompson, and Eleanor Rosch. His work influenced cognitive science, biology, artificial intelligence research, and ecological philosophy.

Key Concepts

Essential Works

  1. “Autopoiesis and Cognition: The Realization of the Living” (D. Reidel, 1980) - ISBN 978-90-277-1015-4 - With Humberto Maturana
  2. “The Tree of Knowledge: The Biological Roots of Human Understanding” (Shambhala, 1987) - ISBN 978-0-87773-642-4 - With Humberto Maturana
  3. “The Embodied Mind: Cognitive Science and Human Experience” (MIT Press, 1991) - ISBN 978-0-262-72021-2 - With Evan Thompson and Eleanor Rosch
  4. “Principles of Biological Autonomy” (North Holland, 1979) - ISBN 978-0-444-00153-7
  5. “Ethical Know-How: Action, Wisdom, and Cognition” (Stanford University Press, 1999) - ISBN 978-0-804-73046-3

Selected Quotes

All doing is knowing, and all knowing is doing. — The Tree of Knowledge (1987)

We do not see the world as it is, we see the world as we are. — The Embodied Mind (1991)

Every act of knowing brings forth a world. — Principles of Biological Autonomy (1979)

The living being and its environment are mutually enfolded in multiple ways, and so what constitutes the world of a given organism is enacted by that organism’s history of structural coupling. — The Embodied Mind (1991)

Autopoiesis is the mechanism that makes living systems autonomous. — Autopoiesis and Cognition (1980)

Cognition is not the representation of a pre-given world by a pre-given mind, but is rather the enactment of a world and a mind. — The Embodied Mind (1991)

Evolution has no purpose; it simply drifts with the only constraint of maintaining structural coupling. — The Tree of Knowledge (1987)

Wisdom consists in being open to the groundlessness of experience. — Ethical Know-How (1999)

“If everybody would agree that their current reality is A reality, and that what we essentially share is our capacity for constructing a reality, then perhaps we could all agree on a meta-agreement for computing a reality that would mean survival and dignity for everyone on the planet, rather than each group being sold on a particular way of doing things.” - quoted on the Global Vision Website


Further Reading

Biographical Sources

Key Books

**On Autopoiesis and cognition
**

Varela,F., H.Maturana and R.Uribe (1974). Autopoiesis: The organization of living systems, its characterization and a model. Biosystems 5:187-196.

Varela,F. (1980).Describing the logic of the living in: M.Zeleny (Ed.), Autopoeisis: A theory of the living organization, North-Holland. New York, pp.36-48.

Varela,F. (1987)The science and technology of cognition: Emergent directions, in: J.L.Roos (Ed.), Economics and Artificial Intelligence, 1st IFAC Intl.Symposium, Pergamon Press, Oxford/New York , pp.1-9.

H.Maturana and F.Varela (1987) The Tree of Knowledge: A new look at the biological roots of human understanding. Shambhala/New Science Library, Boston, 1987

Varela,F.,A.Anderssen, G.Dietrich, A.Sundblad, D.Holmberg, M.Kazatchkine and A. Coutinho (1991) The population dynamics of natural antibodies in normal and autoimmune individuals. Proc.Natl.Acad.Sci. (USA) 88: 5917-5921

Varela F, Lachaux JP, Rodriguez E, Martinerie J (2001). The brainweb: Phase synchronization and large-scale integration. Nature Reviews in Neuroscience 2 (4): 229-239

On Buddhism

J.Hayward and F.Varela (Eds.) Gentle Bridges: Conversations with the Dalai Lama on the Sciences of Mind.. Shambhala Publishers, Boston, 1992

F.Varela (Ed.). Sleeping, Dreaming and Dying: Dialogues between the Sciences and the Buddhist Tradition,, Wisdom Book, Boston, 1997

**On Philosophy **

Varela,F. and J.P.Dupuy (Eds.) Understanding Origin: Scientific Ideas on the Origin of Life, Mind, and Society.(A Stanford University Interational Symposium).Boston Studies Phil.Sci, Kluwer Assoc., Dordrecht, 1992

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